You can not at this time use a keyboard and mouse to play xbox 360 games. there is also the below link to a petition to get MS to inclued KB and Mouse use in games.
Guess I won't be buying an XBOX then. Pity they have no support for folks who can't physically use a game controller.
Xbox 360 Question Keyboard and Mouse support?
in Computer Gaming
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Pity they have no support for folks who can't physically use a game controller.