I don't think the amount of monitors should slow down your computer. I have worked with with computer with as much as 4 monitors connected to one workstation (one video card). I disconnect and reconnect a bunch of these and then test them out. I didn't notice any lag or slowdown at all. On top of that, these are not exactly top notch computers. The main thing you need to do (configuring-wise), is to enable those monitors so they can be extended. Then putting them in a order that's fit for you....left to right, or whatever position your monitors are in.
Having multiple monitors is more than just having more space. It can be a huge time saver for some people...say those on a trading floor. They have mulitple programs opened and each program have it's own monitor. Try doing that on a single monitor at full size for each program...not quite possible if you ask me